Vittaforma corneae n. comb. for the human microsporidium Nosema corneum Shadduck, Meccoli, Davis & Font, 1990, based on its ultrastructure in the liver of experimentally infected athymic mice.
نویسندگان
چکیده
A new genus, Vittaforma n.g. is proposed for the human microsporidium Nosema corneum Shadduck, Meccoli, Davis & Font, 1990, based on the ultrastructure of developmental stages in the liver of experimentally infected athymic mice. The diplokaryotic arrangement of the nuclei is the only character that conforms with the description of the genus Nosema. Sporogony is polysporoblastic, sporonts are ribbon-shaped, constricting to give rise to linear arrays of sporoblasts and each parasite is enveloped by a complete cisterna of host endoplasmic reticulum. Comparison of N. corneum, with established genera revealed that there were none with the same combination of characters. Consequently it is proposed that Nosema corneum be placed in a new genus as Vittaforma corneae n. comb.
منابع مشابه
In vitro cultivation of microsporidia of clinical importance.
Although attempts to develop methods for the in vitro cultivation of microsporidia began as early as 1937, the interest in the culture of these organisms was confined mostly to microsporidia that infect insects. The successful cultivation in 1969 of Encephalitozoon cuniculi, a microsporidium of mammalian origin, and the subsequent identification of these organisms as agents of human disease hei...
متن کاملEvaluation of large-scale dissemination of Nosema ceranae spores by European bee-eaters Merops apiaster.
Identification of transmission routes and of factors affecting the spatial positions of pathogens, hosts and vectors is basic to an adequate disease management. Nosema ceranae is a Microsporidian recently described as a parasite of Apis mellifera honeybees and is currently considered the aetiological agent of an emergent illness named nosemosis type C. In this article we evaluate the role of a ...
متن کاملAnalysis of the beta-tubulin gene from Vittaforma corneae suggests benzimidazole resistance.
We amplified, cloned, and sequenced the beta-tubulin gene of Vittaforma corneae, a microsporidium causing human infections. The beta-tubulin gene sequence has a substitution at Glu(198) (with glutamine), which is one of six amino acids reported to be associated with benzimidazole sensitivity. Benzimidazoles were assayed for antimicrosporidial activity and showed poor parasite inhibition.
متن کاملAnalysis of the -Tubulin Gene from Vittaforma corneae Suggests Benzimidazole Resistance
Microsporidia are obligate intracellular protozoan parasites that have emerged as major opportunistic human pathogens since the onset of the AIDS pandemic (6, 11). Vittaforma corneae is responsible for keratitis in otherwise healthy persons (2, 9, 10, 18), but disseminated infections have occurred in human immunodeficiency virus-infected patients as well (3). V. corneae was first described as N...
متن کاملNosema notabilis (Microsporidia), its ultrastructure and effect on the myxosporean host Ortholinea polymorpha.
Nosema notabilis Kudo, 1939 produces chain-forming meronts with a dense cell coat in direct contact with the host cell cytoplasm. Cytoplasmic microtubules and membranaceous whorls could be observed in meront cytoplasm. Sporonts differ in that they have a thicker cell wall and more conspicuous endoplasmic reticulum (ER) cisternae. Sporoblasts have an externally ridged cell wall. Spores have an a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- The Journal of eukaryotic microbiology
دوره 42 2 شماره
صفحات -
تاریخ انتشار 1995